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How to Change Your Mind: What the New Science of Psychedelics Tea...
by Michael Pollan

Language

English

Pages

474

Publication Date

May 15, 2018

Product Description
Customer Reviews
<b><b><b><b><i>New York Times Book Review</i>聽10 Best Books of 2018</b></b><br /><br />A<i> New York Times </i>Notable Book聽<br /><br />The #1 <i>New York Times</i>聽bestseller.<br /><br />A brilliant and brave investigation聽into the medical and scientific revolution taking place around psychedelic drugs--and the spellbinding story of his own life-changing psychedelic experiences </b></b><br /><br />When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third. Thus began a singular adventure into various altered states of consciousness, along with a dive deep into both the latest brain science and the thriving underground community of psychedelic therapists. Pollan sifts the historical record to separate the truth about these mysterious drugs from the myths that have surrounded them since the 1960s, when a handful of psychedelic evangelists inadvertently catalyzed a powerful backlash against what was then a promising field of research.<br /><br />A unique and elegant blend of science, memoir, travel writing, history, and medicine, <i>How to Change Your Mind</i> is a triumph of participatory journalism. By turns dazzling and edifying, it is the gripping account of a journey to an exciting and unexpected new frontier in our understanding of the mind, the self, and our place in the world. The true subject of Pollan's "mental travelogue" is not just psychedelic drugs but also the eternal puzzle of human consciousness and how, in a world that offers us both suffering and joy, we can do our best to be fully present and find meaning in our lives.
The Radium Girls: The Dark Story of America's Shining Women
by Kate Moore

Language

English

Pages

415

Publication Date

April 18, 2017

Product Description
Customer Reviews
<p><strong>A<em> New York Times</em>, <em>USA Today, </em>and<em> Wall Street Journal</em> Bestseller!</strong><br /><strong>Emma Watson's Our Shared Shelf Bookclub Selection - May/June 2018 </strong></p><p>"<strong>the glowing ghosts of the radium girls haunt us still</strong>."鈥擭PR Books </p><p><em>The incredible true story of the women who fought America's Undark danger</em></p><p>The Curies' newly discovered element of radium makes gleaming headlines across the nation as the fresh face of beauty, and wonder drug of the medical community. From body lotion to tonic water, the popular new element shines bright in the otherwise dark years of the First World War.</p><p>Meanwhile, hundreds of girls toil amidst the glowing dust of the radium-dial factories. The glittering chemical covers their bodies from head to toe; they light up the night like industrious fireflies. With such a coveted job, these "shining girls" are the luckiest alive 鈥?until they begin to fall mysteriously ill.</p><p>But the factories that once offered golden opportunities are now ignoring all claims of the gruesome side effects, and the women's cries of corruption. And as the fatal poison of the radium takes hold, the brave shining girls find themselves embroiled in one of the biggest scandals of America's early 20th century, and in a groundbreaking battle for workers' rights that will echo for centuries to come. </p><p>Written with a sparkling voice and breakneck pace, <em>The Radium Girls</em> fully illuminates the inspiring young women exposed to the "wonder" substance of radium, and their awe-inspiring strength in the face of almost impossible circumstances. Their courage and tenacity led to life-changing regulations, research into nuclear bombing, and ultimately saved hundreds of thousands of lives...</p>
Dopesick: Dealers, Doctors, and the Drug Company that Addicted Am...
by Beth Macy

Language

English

Pages

385

Publication Date

August 07, 2018

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Customer Reviews
<b>An instant <i>New York Times </i>bestseller, <i>Dopesick </i>is the only book to tell the full story of the opioid crisis, from the boardroom to the courtroom and into the living rooms of Americans struggling to save themselves and their families: "masterfully interlaces stories of communities in crisis with dark histories of corporate greed and regulatory indifference" (<i>New York Times</i>) from a journalist who has lived through it.</b><br />In this extraordinary work, Beth Macy takes us into the epicenter of a national drama that has unfolded over two decades. From the labs and marketing departments of big pharma to local doctor's offices; wealthy suburbs to distressed small communities in Central Appalachia; from distant cities to once-idyllic farm towns; the spread of opioid addiction follows a tortuous trajectory that illustrates how this crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy sets out to answer a grieving mother's question-why her only son died-and comes away with a gripping, unputdownable story of greed and need. From the introduction of OxyContin in 1996, Macy investigates the powerful forces that led America's doctors and patients to embrace a medical culture where overtreatment with painkillers became the norm. In some of the same communities featured in her bestselling book <i>Factory Man</i>, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.<br /><br /> Through unsparing, compelling, and unforgettably humane portraits of families and first responders determined to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows that one thing uniting Americans across geographic, partisan, and class lines is opioid drug abuse. But even in the midst of twin crises in drug abuse and healthcare, Macy finds reason to hope and ample signs of the spirit and tenacity that are helping the countless ordinary people ensnared by addiction build a better future for themselves, their families, and their communities.<br /><br /> <b>"An impressive feat of journalism, monumental in scope and urgent in its implications."</b> -<b> Jennifer Latson, <i>The Boston Globe</i></b><br /><br /> <br /><br /><br />
Bottle of Lies: The Inside Story of the Generic Drug Boom
by Katherine Eban

Language

English

Pages

512

Publication Date

May 14, 2019

Product Description
Customer Reviews
<p><strong>A <em>NEW YORK TIMES</em> BESTSELLER </strong></p><p><strong>From an award-winning journalist, an explosive narrative investigation of the generic drug boom that reveals fraud and life-threatening dangers on a global scale鈥?lt;em>The Jungle</em>聽for pharmaceuticals</strong></p><p>Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?</p><p>Katherine Eban鈥檚 <em>Bottle of Lies</em> exposes the deceit behind generic-drug manufacturing鈥攁nd the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.</p><p>The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?聽 </p><p>A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, <em>Bottle of Lies</em> reveals how the world鈥檚 greatest public-health innovation has become one of its most astonishing swindles.</p><p>聽</p>
Fentanyl, Inc.: How Rogue Chemists Are Creating the Deadliest Wav...
by Ben Westhoff

Language

English

Pages

356

Publication Date

September 03, 2019

Product Description
Customer Reviews
A deeply human story, <i>Fentanyl, Inc.</i> is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. 鈥淎 whole new crop of chemicals is radically changing the recreational drug landscape,鈥?writes Ben Westhoff. 鈥淭hese are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs鈥濃€攁nd all-too-often tragically lethal.<p>Drugs like fentanyl, K2, and Spice鈥攁nd those with arcane acronyms like 25i-NBOMe鈥?were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs鈥?effects impossible to predict. Westhoff has infiltrated this shadowy world. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Westhoff visits the shady factories in China from which these drugs emanate, providing startling and original reporting on how China鈥檚 vast chemical industry operates, and how the Chinese government subsidizes it. Poignantly, he chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.</p>
Chronic Renal Disease
by Academic Press

Language

English

Pages

930

Publication Date

September 26, 2014

Product Description
Customer Reviews
<p><i>Chronic Renal Disease</i>聽comprehensively investigates the physiology, pathophysiology, treatment, and management of chronic kidney disease (CKD). This translational reference takes an in-depth look at CKD while excluding coverage of dialysis or transplantation, which are both well detailed in other textbooks and references. Chapters in the basic science sections are devoted to the scientific underpinnings of the development and progression of CKD, including consideration of different etiologic factors. Chapters in the treatment and management sections are geared towards the most common problems faced by nephrologists in the management of CKD. Each chapter relates specific illnesses to the CKD framework instead of covering only the specific illness. Readers will learn, for example, how the management of CKD in a patient with diabetic nephropathy differs from that of other CKD patients. Chapters indicate which unique complications the reader needs to be aware of when treating a specific patient or disease.</p> <p><i>Chronic Renal Disease</i> includes a companion web-based question and answer supplement to each chapter. This is a valuable resource to reinforce the content of the chapters. The questions are multiple-choice, clinically focused and include referenced discussions of answers. The questions can be used for medical student, resident and fellow teaching, preparation for board or maintenance of certification examinations, and clinician teaching or conference preparation.</p><ul><li>Provides a useful resource to professors who need to create lectures for residents and fellows, and to identify and summarize relevant literature as it relates to various research projects</li><li>Includes multiple choice questions and answers, which can be used as a teaching tool for conferences and continuing medical education activities </li><li>Includes coverage of classification and measurement, epidemiology, pathophysiology, complications of CKD, fluid / electrolyte disorders in CKD, CKD and systemic illnesses, clinical considerations, therapeutic considerations, and special considerations</li></ul>
Pharmaceutical Formulation: The Science and Technology of Dosage ...
by Royal Society of Chemistry

Language

English

Pages

409

Publication Date

June 25, 2018

Product Description
Customer Reviews
<p>Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field.</p><br /><p>Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development.</p><br /><p>Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.</p>
Antiarrhythmic Drugs: Mechanisms of Antiarrhythmic and Proarrhyth...
by Springer

Language

English

Pages

410

Publication Date

December 06, 2012

Product Description
Customer Reviews
The past 10 years have seen a remarkable change in the approach to cardiac arrhythmias, from a position of confidence and a feeling of well-being about pharmacological treatment to a situation in which there is now marked uncertainty and general apprehension about the role of antiarrhythmic drugs. Until relatively recently the prevailing concept in antiarrhythmic therapy was that arrhythmias could be controlled by drugs which slowed conduction or suppressed automaticity, goals well served by the sodium channel-blocking drugs and glycosides. Drug re顱 search was based largely on the development of agents mimicking those already available, but with greater efficacy, fewer side effects or a more favourable phar顱 macokinetic profile. The CAST trial stands out as a landmark in the evolution of arrhytmia manage顱 ment; rarely has a single trial had such a profound impact not only on clinical prac顱 tice, but also on the whole approach of those involved in the research, development and regulation of antiarrhythmic drugs. The results of the CAST trial, designed to redress the shortcomings of earlier trials which had failed to demonstrate the anticipated improvement in mortality post-myocardial infarction with the use of class I agents, are well known. The CAST and CAST II showed an increase in mor顱 tality associated with the active agent (encainide, flecainide or morizicine) com顱 pared to placebo treatment. They firmly established the potential danger in the use of class I drugs.
Deep Medicine: How Artificial Intelligence Can Make Healthcare Hu...
by Eric Topol

Language

English

Pages

341

Publication Date

March 12, 2019

Product Description
Customer Reviews
<b>One of America's top doctors reveals how AI will empower physicians and revolutionize patient care </b> <br /> Medicine has become inhuman, to disastrous effect. The doctor-patient relationship--the heart of medicine--is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In <i>Deep Medicine</i>, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality. By freeing physicians from the tasks that interfere with human connection, AI will create space for the real healing that takes place between a doctor who can listen and a patient who needs to be heard. <br /> Innovative, provocative, and hopeful, <i>Deep Medicine</i> shows us how the awesome power of AI can make medicine better, for all the humans involved.
What the Eyes Don't See: A Story of Crisis, Resistance, and Hope ...
by Mona Hanna-Attisha

Language

English

Pages

352

Publication Date

June 19, 2018

Product Description
Customer Reviews
<b><b>A聽<i>NEW YORK TIMES聽</i>NOTABLE BOOK 鈥⒙?lt;/b>The dramatic story of the Flint water crisis, by a relentless physician who stood up to power.</b><br /><br /><b>鈥淪tirring . . . [a] blueprint for all those who believe . . . that 鈥榯he world . . . should be full of people raising their voices.鈥欌€濃€?lt;i>The New York Times</i></b><br /><br /><b>鈥淩evealing, with the gripping intrigue of a Grisham thriller.鈥?鈥?lt;i>O: The Oprah Magazine</i></b><br /><br /> Here is the inspiring story of how Dr. Mona Hanna-Attisha, alongside a team of researchers, parents, friends, and community leaders, discovered that the children of Flint, Michigan, were being exposed to lead in their tap water鈥攁nd then battled her own government and a brutal backlash to expose that truth to the world. Paced like a scientific thriller, <i>What the Eyes Don鈥檛 See </i>reveals how misguided austerity policies, broken democracy, and callous bureaucratic indifference placed an entire city at risk. And at the center of the story is Dr. Mona herself鈥攁n immigrant, doctor, scientist, and mother whose family鈥檚 activist roots inspired her pursuit of justice.<br /><br /> <i>What the Eyes Don鈥檛 See</i> is a riveting account of a shameful disaster that became a tale of hope, the story of a city on the ropes that came together to fight for justice, self-determination, and the right to build a better world for their鈥攁nd all of our鈥攃hildren.<br /><br /><b>Praise for聽<i>What the Eyes Don鈥檛 See</i></b><br /><br />鈥淚t is one thing to point out a problem. It is another thing altogether to step up and work to fix it. Mona Hanna-Attisha is a true American hero.鈥?lt;b>鈥擡rin Brockovich聽</b><br /><br />鈥淎 clarion call to live a life of purpose.鈥?lt;b>鈥?lt;i>The Washington Post</i></b><br /><br />鈥淕ripping . . . entertaining . . . Her book has power precisely because she takes the events she recounts so personally. . . . Moral outrage present on every page.鈥?lt;b>鈥?lt;i>The New York Times Book Review</i></b><br /><br />鈥淧ersonal and emotional. . . She vividly describes the effects of lead poisoning on her young patients. . . . She is at her best when recounting the detective work she undertook after a tip-off about lead levels from a friend. . . . 鈥汧lint will not be defined by this crisis,鈥?vows Ms. Hanna-Attisha.鈥?lt;b>鈥?lt;i>The Economist</i></b><br /><br />鈥淔lint is a public health disaster. But it was Dr. Mona, this caring, tough pediatrican turned detective, who cracked the case.鈥?lt;b>鈥擱achel Maddow</b>

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